Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches

The bone is essential for locomotion, calcium storage, and harboring the hematopoietic stem cells (HSCs) that supply the body with mature blood cells throughout life. HSCs reside at the interface of the bone and bone marrow (BM), where active bone remodeling takes place. Although the cellular compon...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Das, Prosun, Veazey, Kylee J., Van, Hieu T., Kaushik, Saakshi, Lin, Kevin, Lu, Yue, Ishii, Masaru, Kikuta, Junichi, Ge, Kai, Nussenzweig, Andre, Santos, Margarida A.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2018
Предметы:
PNAS Plus
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205459/
https://ncbi.nlm.nih.gov/pubmed/30297393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806019115
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