Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches

The bone is essential for locomotion, calcium storage, and harboring the hematopoietic stem cells (HSCs) that supply the body with mature blood cells throughout life. HSCs reside at the interface of the bone and bone marrow (BM), where active bone remodeling takes place. Although the cellular compon...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Das, Prosun, Veazey, Kylee J., Van, Hieu T., Kaushik, Saakshi, Lin, Kevin, Lu, Yue, Ishii, Masaru, Kikuta, Junichi, Ge, Kai, Nussenzweig, Andre, Santos, Margarida A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205459/
https://ncbi.nlm.nih.gov/pubmed/30297393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806019115
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