Osteocyte calcium signals encode strain magnitude and loading frequency in vivo

Osteocytes are considered to be the major mechanosensory cells of bone, but how osteocytes in vivo process, perceive, and respond to mechanical loading remains poorly understood. Intracellular calcium (Ca(2+)) signaling resulting from mechanical stimulation has been widely studied in osteocytes in v...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Lewis, Karl J., Frikha-Benayed, Dorra, Louie, Joyce, Stephen, Samuel, Spray, David C., Thi, Mia M., Seref-Ferlengez, Zeynep, Majeska, Robert J., Weinbaum, Sheldon, Schaffler, Mitchell B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676898/
https://ncbi.nlm.nih.gov/pubmed/29078317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707863114
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