Osteocyte calcium signals encode strain magnitude and loading frequency in vivo

Osteocytes are considered to be the major mechanosensory cells of bone, but how osteocytes in vivo process, perceive, and respond to mechanical loading remains poorly understood. Intracellular calcium (Ca(2+)) signaling resulting from mechanical stimulation has been widely studied in osteocytes in v...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lewis, Karl J., Frikha-Benayed, Dorra, Louie, Joyce, Stephen, Samuel, Spray, David C., Thi, Mia M., Seref-Ferlengez, Zeynep, Majeska, Robert J., Weinbaum, Sheldon, Schaffler, Mitchell B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676898/
https://ncbi.nlm.nih.gov/pubmed/29078317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707863114
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