Osteocyte calcium signals encode strain magnitude and loading frequency in vivo

Osteocytes are considered to be the major mechanosensory cells of bone, but how osteocytes in vivo process, perceive, and respond to mechanical loading remains poorly understood. Intracellular calcium (Ca(2+)) signaling resulting from mechanical stimulation has been widely studied in osteocytes in v...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lewis, Karl J., Frikha-Benayed, Dorra, Louie, Joyce, Stephen, Samuel, Spray, David C., Thi, Mia M., Seref-Ferlengez, Zeynep, Majeska, Robert J., Weinbaum, Sheldon, Schaffler, Mitchell B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676898/
https://ncbi.nlm.nih.gov/pubmed/29078317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707863114
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