Estrogen Depletion on In vivo Osteocyte Calcium Signaling Responses to Mechanical Loading

Microstructural adaptation of bone in response to mechanical stimuli is diminished with estrogen deprivation. Here we tested in vivo whether ovariectomy (OVX) alters the acute response of osteocytes, the principal mechanosensory cells of bone, to mechanical loading in mice. We also used super resolu...

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Vydáno v:Bone
Hlavní autoři: Lewis, Karl J, Cabahug Zuckerman, Pamela, Boorman-Padgett, James F, Basta-Pljakic, Jelena, Louie, Joyce, Stephen, Samuel, Spray, David C, Thi, Mia M, Seref-Ferlengez, Zeynep, Majeska, Robert J, Weinbaum, Sheldon, Schaffler, Mitchell B
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316427/
https://ncbi.nlm.nih.gov/pubmed/34171514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2021.116072
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