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A method for measuring the distribution of the shortest telomeres in cells and tissues

Improved methods to measure the shortest (not just average) telomere lengths (TLs) are needed. We developed Telomere Shortest Length Assay (TeSLA), a technique that detects telomeres from all chromosome ends from <1 kb to 18 kb using small amounts of input DNA. TeSLA improves the specificity and...

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Publicat a:Nat Commun
Autors principals: Lai, Tsung-Po, Zhang, Ning, Noh, Jungsik, Mender, Ilgen, Tedone, Enzo, Huang, Ejun, Wright, Woodring E., Danuser, Gaudenz, Shay, Jerry W.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676791/
https://ncbi.nlm.nih.gov/pubmed/29116081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01291-z
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