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Telomere length and telomerase activity in T cells are biomarkers of high‐performing centenarians

It is generally recognized that the function of the immune system declines with increased age and one of the major immune changes is impaired T‐cell responses upon antigen presentation/stimulation. Some “high‐performing” centenarians (100+ years old) are remarkably successful in escaping, or largely...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Tedone, Enzo, Huang, Ejun, O’Hara, Ryan, Batten, Kimberly, Ludlow, Andrew T., Lai, Tsung‐Po, Arosio, Beatrice, Mari, Daniela, Wright, Woodring E., Shay, Jerry W.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351827/
https://ncbi.nlm.nih.gov/pubmed/30488553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12859
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