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Telomere length and telomerase activity in T cells are biomarkers of high‐performing centenarians

It is generally recognized that the function of the immune system declines with increased age and one of the major immune changes is impaired T‐cell responses upon antigen presentation/stimulation. Some “high‐performing” centenarians (100+ years old) are remarkably successful in escaping, or largely...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Aging Cell
Hauptverfasser: Tedone, Enzo, Huang, Ejun, O’Hara, Ryan, Batten, Kimberly, Ludlow, Andrew T., Lai, Tsung‐Po, Arosio, Beatrice, Mari, Daniela, Wright, Woodring E., Shay, Jerry W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351827/
https://ncbi.nlm.nih.gov/pubmed/30488553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12859
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