Telomere length and telomerase activity in T cells are biomarkers of high‐performing centenarians

It is generally recognized that the function of the immune system declines with increased age and one of the major immune changes is impaired T‐cell responses upon antigen presentation/stimulation. Some “high‐performing” centenarians (100+ years old) are remarkably successful in escaping, or largely...

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Bibliografske podrobnosti
izdano v:Aging Cell
Main Authors: Tedone, Enzo, Huang, Ejun, O’Hara, Ryan, Batten, Kimberly, Ludlow, Andrew T., Lai, Tsung‐Po, Arosio, Beatrice, Mari, Daniela, Wright, Woodring E., Shay, Jerry W.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351827/
https://ncbi.nlm.nih.gov/pubmed/30488553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12859
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