Quantitative mitochondrial DNA copy number determination using droplet digital PCR with single-cell resolution

Mitochondria are involved in a number of diverse cellular functions, including energy production, metabolic regulation, apoptosis, calcium homeostasis, cell proliferation, and motility, as well as free radical generation. Mitochondrial DNA (mtDNA) is present at hundreds to thousands of copies per ce...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: O'Hara, Ryan, Tedone, Enzo, Ludlow, Andrew, Huang, Ejun, Arosio, Beatrice, Mari, Daniela, Shay, Jerry W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6836731/
https://ncbi.nlm.nih.gov/pubmed/31548359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.250480.119
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