Quantitative mitochondrial DNA copy number determination using droplet digital PCR with single-cell resolution

Mitochondria are involved in a number of diverse cellular functions, including energy production, metabolic regulation, apoptosis, calcium homeostasis, cell proliferation, and motility, as well as free radical generation. Mitochondrial DNA (mtDNA) is present at hundreds to thousands of copies per ce...

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Bibliographic Details
Published in:Genome Res
Main Authors: O'Hara, Ryan, Tedone, Enzo, Ludlow, Andrew, Huang, Ejun, Arosio, Beatrice, Mari, Daniela, Shay, Jerry W.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2019
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Method
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6836731/
https://ncbi.nlm.nih.gov/pubmed/31548359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.250480.119
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