High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number

[Image: see text] Digital PCR enables the absolute quantitation of nucleic acids in a sample. The lack of scalable and practical technologies for digital PCR implementation has hampered the widespread adoption of this inherently powerful technique. Here we describe a high-throughput droplet digital...

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Detalhes bibliográficos
Main Authors: Hindson, Benjamin J., Ness, Kevin D., Masquelier, Donald A., Belgrader, Phillip, Heredia, Nicholas J., Makarewicz, Anthony J., Bright, Isaac J., Lucero, Michael Y., Hiddessen, Amy L., Legler, Tina C., Kitano, Tyler K., Hodel, Michael R., Petersen, Jonathan F., Wyatt, Paul W., Steenblock, Erin R., Shah, Pallavi H., Bousse, Luc J., Troup, Camille B., Mellen, Jeffrey C., Wittmann, Dean K., Erndt, Nicholas G., Cauley, Thomas H., Koehler, Ryan T., So, Austin P., Dube, Simant, Rose, Klint A., Montesclaros, Luz, Wang, Shenglong, Stumbo, David P., Hodges, Shawn P., Romine, Steven, Milanovich, Fred P., White, Helen E., Regan, John F., Karlin-Neumann, George A., Hindson, Christopher M., Saxonov, Serge, Colston, Bill W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2011
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216358/
https://ncbi.nlm.nih.gov/pubmed/22035192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac202028g
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