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Imaging assay to probe the role of telomere length shortening on telomere-gene interactions in single cells

Telomeres are repetitive non-coding nucleotide sequences (TTAGGGn) capping the ends of chromosomes. Progressive telomere shortening with increasing age has been associated with shifts in gene expression through models such as the telomere position effect (TPE), which suggests reduced interference of...

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發表在:Chromosoma
Main Authors: Zhang, Ning, Li, Yanhui, Lai, Tsung-Po, Shay, Jerry W., Danuser, Gaudenz
格式: Artigo
語言:Inglês
出版: Springer Berlin Heidelberg 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889534/
https://ncbi.nlm.nih.gov/pubmed/33555479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-020-00747-4
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