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Imaging assay to probe the role of telomere length shortening on telomere-gene interactions in single cells

Telomeres are repetitive non-coding nucleotide sequences (TTAGGGn) capping the ends of chromosomes. Progressive telomere shortening with increasing age has been associated with shifts in gene expression through models such as the telomere position effect (TPE), which suggests reduced interference of...

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Bibliografiske detaljer
Udgivet i:Chromosoma
Main Authors: Zhang, Ning, Li, Yanhui, Lai, Tsung-Po, Shay, Jerry W., Danuser, Gaudenz
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889534/
https://ncbi.nlm.nih.gov/pubmed/33555479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-020-00747-4
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