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Imaging assay to probe the role of telomere length shortening on telomere-gene interactions in single cells

Telomeres are repetitive non-coding nucleotide sequences (TTAGGGn) capping the ends of chromosomes. Progressive telomere shortening with increasing age has been associated with shifts in gene expression through models such as the telomere position effect (TPE), which suggests reduced interference of...

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Bibliografiska uppgifter
I publikationen:Chromosoma
Huvudupphovsmän: Zhang, Ning, Li, Yanhui, Lai, Tsung-Po, Shay, Jerry W., Danuser, Gaudenz
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Berlin Heidelberg 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889534/
https://ncbi.nlm.nih.gov/pubmed/33555479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-020-00747-4
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