Decreasing initial telomere length in humans intergenerationally understates age-associated telomere shortening

Telomere length shortens with aging, and short telomeres have been linked to a wide variety of pathologies. Previous studies suggested a discrepancy in age-associated telomere shortening rate estimated by cross-sectional studies versus the rate measured in longitudinal studies, indicating a potentia...

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Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Holohan, Brody, De Meyer, Tim, Batten, Kimberly, Mangino, Massimo, Hunt, Steven C, Bekaert, Sofie, De Buyzere, Marc L, Rietzschel, Ernst R, Spector, Tim D, Wright, Woodring E, Shay, Jerry W
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Ltd 2015
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531080/
https://ncbi.nlm.nih.gov/pubmed/25952108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12347
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