Telomere position effect: regulation of gene expression with progressive telomere shortening over long distances

While global chromatin conformation studies are emerging, very little is known about the chromatin conformation of human telomeres. Most studies have focused on the role of telomeres as a tumor suppressor mechanism. Here we describe how telomere length regulates gene expression long before telomeres...

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Pubblicato in:Genes Dev
Autori principali: Robin, Jérôme D., Ludlow, Andrew T., Batten, Kimberly, Magdinier, Frédérique, Stadler, Guido, Wagner, Kathyrin R., Shay, Jerry W., Wright, Woodring E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2014
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233240/
https://ncbi.nlm.nih.gov/pubmed/25403178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.251041.114
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