Telomere position effect: regulation of gene expression with progressive telomere shortening over long distances

While global chromatin conformation studies are emerging, very little is known about the chromatin conformation of human telomeres. Most studies have focused on the role of telomeres as a tumor suppressor mechanism. Here we describe how telomere length regulates gene expression long before telomeres...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Robin, Jérôme D., Ludlow, Andrew T., Batten, Kimberly, Magdinier, Frédérique, Stadler, Guido, Wagner, Kathyrin R., Shay, Jerry W., Wright, Woodring E.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2014
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233240/
https://ncbi.nlm.nih.gov/pubmed/25403178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.251041.114
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