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A method for measuring the distribution of the shortest telomeres in cells and tissues

Improved methods to measure the shortest (not just average) telomere lengths (TLs) are needed. We developed Telomere Shortest Length Assay (TeSLA), a technique that detects telomeres from all chromosome ends from <1 kb to 18 kb using small amounts of input DNA. TeSLA improves the specificity and...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lai, Tsung-Po, Zhang, Ning, Noh, Jungsik, Mender, Ilgen, Tedone, Enzo, Huang, Ejun, Wright, Woodring E., Danuser, Gaudenz, Shay, Jerry W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676791/
https://ncbi.nlm.nih.gov/pubmed/29116081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01291-z
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