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Sequence determinants of the conformational properties of an intrinsically disordered protein prior to and upon multisite phosphorylation
Many cell signaling events are coordinated by intrinsically disordered protein regions (IDRs) that undergo multisite Serine/Threonine phosphorylation. The conformational properties of these IDRs prior to and following multi-site phosphorylation are directly relevant to understanding their functions....
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| Veröffentlicht in: | J Am Chem Soc |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5675102/ https://ncbi.nlm.nih.gov/pubmed/27807972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b10272 |
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