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Sequence determinants of the conformational properties of an intrinsically disordered protein prior to and upon multisite phosphorylation

Many cell signaling events are coordinated by intrinsically disordered protein regions (IDRs) that undergo multisite Serine/Threonine phosphorylation. The conformational properties of these IDRs prior to and following multi-site phosphorylation are directly relevant to understanding their functions....

詳細記述

保存先:
書誌詳細
出版年:J Am Chem Soc
主要な著者: Martin, Erik W., Holehouse, Alex S., Grace, Christy R., Hughes, Alex, Pappu, Rohit V., Mittag, Tanja
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675102/
https://ncbi.nlm.nih.gov/pubmed/27807972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b10272
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