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Sequence determinants of the conformational properties of an intrinsically disordered protein prior to and upon multisite phosphorylation

Many cell signaling events are coordinated by intrinsically disordered protein regions (IDRs) that undergo multisite Serine/Threonine phosphorylation. The conformational properties of these IDRs prior to and following multi-site phosphorylation are directly relevant to understanding their functions....

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Podrobná bibliografie
Vydáno v:J Am Chem Soc
Hlavní autoři: Martin, Erik W., Holehouse, Alex S., Grace, Christy R., Hughes, Alex, Pappu, Rohit V., Mittag, Tanja
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675102/
https://ncbi.nlm.nih.gov/pubmed/27807972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b10272
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