N-Myc-Interacting Protein Negatively Regulates TNF-α-Induced NF-κB Transcriptional Activity by Sequestering NF-κB/p65 in the Cytoplasm

NF-κB is a major regulator of gene transcription involved in immune, inflammation, apoptosis and stress responses. However, the regulation of NF-κB is not completely understood. Here, we report that the N-Myc and STATs Interactor (NMI), an IFN-inducible protein, is an important negative regulator of...

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Publicado en:Sci Rep
Autores principales: Hou, Jingjing, Jiang, Shihao, Zhao, Jiabao, Zhu, Dong, Zhao, Xinmeng, Cai, Jian-chun, Zhang, Si Qing
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674077/
https://ncbi.nlm.nih.gov/pubmed/29109532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15074-5
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