USP11 Negatively Regulates TNFα-Induced NF-κB Activation by Targeting on IκBα

IκBα serves as a central anchoring molecule in the sequestration of NF-κB transcription factor in the cytoplasm. Ubiquitination-mediated IκBα degradation immediately precedes and is required for NF-κB nuclear translocation and activation. However, the precise mechanism for the deubiquitination of Iκ...

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Autores principales: Sun, Wenjing, Tan, Xiaojie, Shi, Yi, Xu, Gufeng, Mao, Renfang, Gu, Xue, Fan, Yihui, Yu, Yang, Burlingame, Susan, Zhang, Hong, Rednam, Surya P., Lu, Xiongbin, Zhang, Ting, Fu, Songbin, Cao, Guangwen, Qin, Jun, Yang, Jianhua
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794974/
https://ncbi.nlm.nih.gov/pubmed/19874889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.10.008
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