PPM1A and PPM1B act as IKKβ phosphatases to terminate TNFα-induced IKKβ-NF-κB activation

IKKβ serves as a central intermediate signaling molecule in the activation of the NF-κB pathway. However, the precise mechanism for the termination of IKKβ activity is still not fully understood. Using a functional genomic approach, we have identified two protein serine/threonine phosphatases, PPM1A...

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Detalhes bibliográficos
Main Authors: Sun, Wenjing, Yu, Yang, Dotti, Gianpietro, Shen, Tao, Tan, Xiaojie, Savoldo, Barbara, Pass, Amy K., Chu, Meijin, Zhang, Dekai, Lu, Xiongbin, Fu, Songbin, Lin, Xia, Yang, Jianhua
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658596/
https://ncbi.nlm.nih.gov/pubmed/18930133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2008.09.012
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