Ubiquitin-specific Peptidase 21 Inhibits Tumor Necrosis Factor α-induced Nuclear Factor κB Activation via Binding to and Deubiquitinating Receptor-interacting Protein 1

Ubiquitination and deubiquitination of receptor-interacting protein 1 (RIP1) play an important role in the positive and negative regulation of the tumor necrosis factor α (TNFα)-induced nuclear factor κB (NF-κB) activation. Using a combination of functional genomic and proteomic approaches, we have...

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Detalhes bibliográficos
Main Authors: Xu, Gufeng, Tan, Xiaojie, Wang, Hongmei, Sun, Wenjing, Shi, Yi, Burlingame, Susan, Gu, Xue, Cao, Guangwen, Zhang, Ting, Qin, Jun, Yang, Jianhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801298/
https://ncbi.nlm.nih.gov/pubmed/19910467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.042689
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