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Positive and negative regulation of EAAT2 by NF-κB: a role for N-myc in TNFα-controlled repression

The glutamate transporter gene, EAAT2/GLT-1, is induced by epidermal growth factor (EGF) and downregulated by tumor necrosis factor α (TNFα). While TNFα is generally recognized as a positive regulator of NF-κB-dependent gene expression, its ability to control transcriptional repression is not well c...

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Hlavní autoři: Sitcheran, Raquel, Gupta, Pankaj, Fisher, Paul B, Baldwin, Albert S
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC548660/
https://ncbi.nlm.nih.gov/pubmed/15660126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600555
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