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Positive and negative regulation of EAAT2 by NF-κB: a role for N-myc in TNFα-controlled repression
The glutamate transporter gene, EAAT2/GLT-1, is induced by epidermal growth factor (EGF) and downregulated by tumor necrosis factor α (TNFα). While TNFα is generally recognized as a positive regulator of NF-κB-dependent gene expression, its ability to control transcriptional repression is not well c...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC548660/ https://ncbi.nlm.nih.gov/pubmed/15660126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600555 |
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