Negative regulation of NF-κB p65 activity by serine 536 phosphorylation

Nuclear factor κB (NF-κB) is a master regulator of inflammation and cell death. Whereas most of the activity of NF-κB is regulated through the inhibitor of kB (IκB) kinase (IKK)–dependent degradation of IκB, IKK also phosphorylates subunits of NF-κB. Here, we investigated the contribution of the pho...

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Bibliographic Details
Published in:	Sci Signal
Main Authors:	Pradère, Jean-Philippe, Hernandez, Céline, Koppe, Christiane, Friedman, Richard A, Luedde, Tom, Schwabe, Robert F.
Format:	Artigo
Language:	Inglês
Published:	2016
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5327697/ https://ncbi.nlm.nih.gov/pubmed/27555662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aab2820
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Negative regulation of NF-κB p65 activity by serine 536 phosphorylation

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