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Trovafloxacin acyl-glucuronide induces chemokine (C-X-C motif) ligand 2 in HepG2 cells

UDP-glucuronosyltransferases (UGTs) catalyze glucuronidation of endogenous and exogenous compounds by transferring the glucuronic acid moiety of UDP-glucuronic acid to the substrates. While glucuronides are usually pharmacologically inactive, certain types of glucuronides, especially acyl-glucuronid...

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Detalhes bibliográficos
Publicado no:Biol Pharm Bull
Main Authors: Mitsugi, Ryo, Sumida, Kyohei, Fujie, Yoshiko, Tukey, Robert H., Itoh, Tomoo, Fujiwara, Ryoichi
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673480/
https://ncbi.nlm.nih.gov/pubmed/27725437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1248/bpb.b16-00195
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