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Trovafloxacin acyl-glucuronide induces chemokine (C-X-C motif) ligand 2 in HepG2 cells

UDP-glucuronosyltransferases (UGTs) catalyze glucuronidation of endogenous and exogenous compounds by transferring the glucuronic acid moiety of UDP-glucuronic acid to the substrates. While glucuronides are usually pharmacologically inactive, certain types of glucuronides, especially acyl-glucuronid...

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Bibliografische gegevens
Gepubliceerd in:Biol Pharm Bull
Hoofdauteurs: Mitsugi, Ryo, Sumida, Kyohei, Fujie, Yoshiko, Tukey, Robert H., Itoh, Tomoo, Fujiwara, Ryoichi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673480/
https://ncbi.nlm.nih.gov/pubmed/27725437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1248/bpb.b16-00195
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