Serine Proteases Enhance Immunogenic Antigen Presentation on Lung Cancer Cells

Immunotherapies targeting immune checkpoints have proven efficacious in reducing the burden of lung cancer in patients; however, the antigenic targets of these re-invigorated T cells remain poorly defined. Lung cancer tumors contain tumor-associated macrophages (TAM) and neutrophils, which release t...

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Publicat a:Cancer Immunol Res
Autors principals: Peters, Haley L., Tripathi, Satyendra C., Kerros, Celine, Katayama, Hiroyuki, Garber, Haven R., St. John, Lisa S., Federico, Lorenzo, Meraz, Ismail M., Roth, Jack A., Sepesi, Boris, Majidi, Mourad, Ruisaard, Kathryn, Clise-Dwyer, Karen, Roszik, Jason, Gibbons, Don L., Heymach, John V., Swisher, Stephen G., Bernantchez, Chantale, Alatrash, Gheath, Hanash, Samir, Molldrem, Jeffrey J.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673248/
https://ncbi.nlm.nih.gov/pubmed/28254787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0141
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