Neuropilin-1 mediates neutrophil elastase uptake and cross-presentation in breast cancer cells

Neutrophil elastase (NE) can be rapidly taken up by tumor cells that lack endogenous NE expression, including breast cancer, which results in cross-presentation of PR1, an NE-derived HLA-A2-restricted peptide that is an immunotherapy target in hematological and solid tumor malignancies. The mechanis...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kerros, Celine, Tripathi, Satyendra C., Zha, Dongxing, Mehrens, Jennifer M., Sergeeva, Anna, Philips, Anne V., Qiao, Na, Peters, Haley L., Katayama, Hiroyuki, Sukhumalchandra, Pariya, Ruisaard, Kathryn E., Perakis, Alexander A., St. John, Lisa S., Lu, Sijie, Mittendorf, Elizabeth A., Clise-Dwyer, Karen, Herrmann, Amanda C., Alatrash, Gheath, Toniatti, Carlo, Hanash, Samir M., Ma, Qing, Molldrem, Jeffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473232/
https://ncbi.nlm.nih.gov/pubmed/28468826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.773051
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados