Membrane-Associated Proteinase 3 on Granulocytes and Acute Myeloid Leukemia Inhibits T Cell Proliferation

Proteinase 3 (P3), a serine protease expressed by myeloid cells, localized within azurophil granules, and also expressed on the cellular membrane of polymorphonuclear neutrophils (PMN), is the target of autoimmunity in granulomatosis with polyangiitis. PR1, an HLA-A2 restricted nonameric peptide der...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Yang, Tian-Hui, St. John, Lisa S., Garber, Haven R., Kerros, Celine, Ruisaard, Kathryn E., Clise-Dwyer, Karen, Alatrash, Gheath, Ma, Qing, Molldrem, Jeffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2018
Assuntos:
Immune Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099529/
https://ncbi.nlm.nih.gov/pubmed/30021768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800324
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