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An anti–PR1/HLA-A2 T-cell receptor–like antibody mediates complement-dependent cytotoxicity against acute myeloid leukemia progenitor cells

PR1 (VLQELNVTV) is a human leukocyte antigen-A2 (HLA-A2)–restricted leukemia-associated peptide from proteinase 3 (P3) and neutrophil elastase (NE) that is recognized by PR1-specific cytotoxic T lymphocytes that contribute to cytogenetic remission of acute myeloid leukemia (AML). We report a novel T...

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Detalhes bibliográficos
Main Authors: Sergeeva, Anna, Alatrash, Gheath, He, Hong, Ruisaard, Kathryn, Lu, Sijie, Wygant, James, McIntyre, Bradley W., Ma, Qing, Li, Dan, St John, Lisa, Clise-Dwyer, Karen, Molldrem, Jeffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087478/
https://ncbi.nlm.nih.gov/pubmed/21296998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-07-299248
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