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Local epigenetic reprograming induced by G-quadruplex ligands

DNA and histone modifications regulate transcriptional activity and thus represent valuable targets to reprogram the activity of genes. Current epigenetic therapies target the machinery that regulates these modifications, leading to global transcriptional reprogramming with the potential for extensi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Chem
Päätekijät: Guilbaud, Guillaume, Murat, Pierre, Recolin, Bénédicte, Campbell, Beth C., Maiter, Ahmed, Sale, Julian E., Balasubramanian, Shankar
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669467/
https://ncbi.nlm.nih.gov/pubmed/29064488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2828
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