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Local epigenetic reprograming induced by G-quadruplex ligands
DNA and histone modifications regulate transcriptional activity and thus represent valuable targets to reprogram the activity of genes. Current epigenetic therapies target the machinery that regulates these modifications, leading to global transcriptional reprogramming with the potential for extensi...
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| Publicado no: | Nat Chem |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5669467/ https://ncbi.nlm.nih.gov/pubmed/29064488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2828 |
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