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Light-mediated in cell downregulation of G-quadruplex-containing genes using a photo-caged ligand
The use of a caged G-quadruplex ligand allows for transcriptional control of quadruplex-containing genes using UV light as an external trigger. An important oncogene, SRC, involved in the initiation and proliferation of epithelial tumours is shown to be significantly downregulated in cells treated b...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4155816/ https://ncbi.nlm.nih.gov/pubmed/23949446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc44737e |
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