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Determinants of G quadruplex-induced epigenetic instability in REV1-deficient cells
REV1-deficient chicken DT40 cells are compromised in replicating G quadruplex (G4)-forming DNA. This results in localised, stochastic loss of parental chromatin marks and changes in gene expression. We previously proposed that this epigenetic instability arises from G4-induced replication fork stall...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4282387/ https://ncbi.nlm.nih.gov/pubmed/25190518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488398 |
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