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Determinants of G quadruplex-induced epigenetic instability in REV1-deficient cells
REV1-deficient chicken DT40 cells are compromised in replicating G quadruplex (G4)-forming DNA. This results in localised, stochastic loss of parental chromatin marks and changes in gene expression. We previously proposed that this epigenetic instability arises from G4-induced replication fork stall...
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| Publié dans: | EMBO J |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BlackWell Publishing Ltd
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4282387/ https://ncbi.nlm.nih.gov/pubmed/25190518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488398 |
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