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Spontaneous Germinal Centers and Autoimmunity
Germinal centers (GCs) are dynamic microenvironments that form in the secondary lymphoid organs and generate somatically mutated high-affinity antibodies necessary to establish an effective humoral immune response. Tight regulation of GC responses is critical for maintaining self-tolerance. GCs can...
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| Veröffentlicht in: | Autoimmunity |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5669068/ https://ncbi.nlm.nih.gov/pubmed/28166685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/08916934.2017.1280671 |
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