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Spontaneous Germinal Centers and Autoimmunity

Germinal centers (GCs) are dynamic microenvironments that form in the secondary lymphoid organs and generate somatically mutated high-affinity antibodies necessary to establish an effective humoral immune response. Tight regulation of GC responses is critical for maintaining self-tolerance. GCs can...

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Detalhes bibliográficos
Publicado no:Autoimmunity
Main Authors: Domeier, Phillip P., Schell, Stephanie L., Rahman, Ziaur S.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669068/
https://ncbi.nlm.nih.gov/pubmed/28166685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/08916934.2017.1280671
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