Llwytho...

B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers

Spontaneous germinal center (Spt-GC) B cells and follicular helper T cells (Tfh) generate high affinity autoantibodies involved in the development of systemic lupus erythematosus (SLE). Toll like receptors (TLRs) play a pivotal role in SLE pathogenesis. While previous studies have focused on the B c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Soni, Chetna, Wong, Eric B., Domeier, Phillip P., Khan, Tahsin N., Satoh, Takashi, Akira, Shizuo, Rahman, Ziaur S.M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201954/
https://ncbi.nlm.nih.gov/pubmed/25252960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401720
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