Structure–Function Relationships Underlying the Capacity of Bordetella Adenylate Cyclase Toxin to Disarm Host Phagocytes

Bordetellae, pathogenic to mammals, produce an immunomodulatory adenylate cyclase toxin–hemolysin (CyaA, ACT or AC-Hly) that enables them to overcome the innate immune defense of the host. CyaA subverts host phagocytic cells by an orchestrated action of its functional domains, where an extremely cat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Toxins (Basel)
Prif Awduron: Novak, Jakub, Cerny, Ondrej, Osickova, Adriana, Linhartova, Irena, Masin, Jiri, Bumba, Ladislav, Sebo, Peter, Osicka, Radim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2017
Pynciau:
Review
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666347/
https://ncbi.nlm.nih.gov/pubmed/28946636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9100300
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