Disease‐modifying effects of ganglioside GM1 in Huntington's disease models

Huntington's disease (HD) is a progressive neurodegenerative disorder characterized by motor, cognitive and psychiatric problems. Previous studies indicated that levels of brain gangliosides are lower than normal in HD models and that administration of exogenous ganglioside GM1 corrects motor d...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO Mol Med
Prif Awduron: Alpaugh, Melanie, Galleguillos, Danny, Forero, Juan, Morales, Luis Carlos, Lackey, Sebastian W, Kar, Preeti, Di Pardo, Alba, Holt, Andrew, Kerr, Bradley J, Todd, Kathryn G, Baker, Glen B, Fouad, Karim, Sipione, Simonetta
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2017
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666311/
https://ncbi.nlm.nih.gov/pubmed/28993428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201707763
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