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Disease‐modifying effects of ganglioside GM1 in Huntington's disease models

Huntington's disease (HD) is a progressive neurodegenerative disorder characterized by motor, cognitive and psychiatric problems. Previous studies indicated that levels of brain gangliosides are lower than normal in HD models and that administration of exogenous ganglioside GM1 corrects motor d...

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Dettagli Bibliografici
Pubblicato in:EMBO Mol Med
Autori principali: Alpaugh, Melanie, Galleguillos, Danny, Forero, Juan, Morales, Luis Carlos, Lackey, Sebastian W, Kar, Preeti, Di Pardo, Alba, Holt, Andrew, Kerr, Bradley J, Todd, Kathryn G, Baker, Glen B, Fouad, Karim, Sipione, Simonetta
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666311/
https://ncbi.nlm.nih.gov/pubmed/28993428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201707763
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