Disease‐modifying effects of ganglioside GM1 in Huntington's disease models

Huntington's disease (HD) is a progressive neurodegenerative disorder characterized by motor, cognitive and psychiatric problems. Previous studies indicated that levels of brain gangliosides are lower than normal in HD models and that administration of exogenous ganglioside GM1 corrects motor d...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Alpaugh, Melanie, Galleguillos, Danny, Forero, Juan, Morales, Luis Carlos, Lackey, Sebastian W, Kar, Preeti, Di Pardo, Alba, Holt, Andrew, Kerr, Bradley J, Todd, Kathryn G, Baker, Glen B, Fouad, Karim, Sipione, Simonetta
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666311/
https://ncbi.nlm.nih.gov/pubmed/28993428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201707763
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