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Impaired Ganglioside Metabolism in Huntington's Disease and Neuroprotective Role of GM1
Huntington's disease (HD) is a neurodegenerative disorder caused by the expansion of a polyglutamine stretch in the protein huntingtin (Htt). HD neurons are dysfunctional at multiple levels and have increased susceptibility to stress and apoptotic stimuli. We have discovered that synthesis of t...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Neurosci |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Society for Neuroscience
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6632269/ https://ncbi.nlm.nih.gov/pubmed/20237277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6348-09.2010 |
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