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Persistent detection of alternatively spliced BCR‐ABL variant results in a failure to achieve deep molecular response
Treatment with tyrosine kinase inhibitors (TKI) may sequentially induce TKI‐resistant BCR‐ABL mutants in chronic myeloid leukemia (CML). Conventional PCR monitoring of BCR‐ABL is an important indicator to determine therapeutic intervention for preventing disease progression. However, PCR cannot sepa...
Guardat en:
| Publicat a: | Cancer Sci |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5666036/ https://ncbi.nlm.nih.gov/pubmed/28801986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13353 |
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