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Persistent detection of alternatively spliced BCR‐ABL variant results in a failure to achieve deep molecular response
Treatment with tyrosine kinase inhibitors (TKI) may sequentially induce TKI‐resistant BCR‐ABL mutants in chronic myeloid leukemia (CML). Conventional PCR monitoring of BCR‐ABL is an important indicator to determine therapeutic intervention for preventing disease progression. However, PCR cannot sepa...
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| 出版年: | Cancer Sci |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5666036/ https://ncbi.nlm.nih.gov/pubmed/28801986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13353 |
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