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Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias
Chronic myelogenous leukemia is a myeloproliferative disorder (MPD) that, over time, progresses to acute leukemia. Both processes are closely associated with the t(9;22) chromosomal translocation that creates the BCR/ABL fusion gene in hematopoietic stem cells (HSCs) and their progeny. Chronic myelo...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC187741/ https://ncbi.nlm.nih.gov/pubmed/12890867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1633833100 |
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