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Two distinct pathways of positive selection for thymocytes

Most mouse thymocytes undergoing positive selection are found on one of two pathways; the c-Kit(+) and the c-Kit(−) pathways. Here, we show that c-Kit and interleukin-7 receptor (IL-7R)-mediated signals support positive selection during the transition from the subpopulation that first expresses cell...

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Detalhes bibliográficos
Main Authors: Akashi, Koichi, Kondo, Motonari, Weissman, Irving L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC19384/
https://ncbi.nlm.nih.gov/pubmed/9482912
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