Isolation of a yeast artificial chromosome spanning the 8;21 translocation breakpoint t(8;21)(q22;q22.3) in acute myelogenous leukemia.

The 8;21 translocation is one of the most common specific rearrangements in acute myelogenous leukemia. We have identified markers (D21S65 and a Not I boundary clone, Not-42, referred to as probe B) flanking the chromosome 21 translocation breakpoint (21q22.3) that demonstrate physical linkage in no...

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Bibliographic Details
Main Authors: Gao, J, Erickson, P, Gardiner, K, Le Beau, M M, Diaz, M O, Patterson, D, Rowley, J D, Drabkin, H A
Format: Artigo
Language:Inglês
Published: 1991
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC51771/
https://ncbi.nlm.nih.gov/pubmed/2052570
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