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Two distinct pathways of positive selection for thymocytes

Most mouse thymocytes undergoing positive selection are found on one of two pathways; the c-Kit(+) and the c-Kit(−) pathways. Here, we show that c-Kit and interleukin-7 receptor (IL-7R)-mediated signals support positive selection during the transition from the subpopulation that first expresses cell...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Akashi, Koichi, Kondo, Motonari, Weissman, Irving L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1998
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19384/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9482912/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.5.2486
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