Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias
Chronic myelogenous leukemia is a myeloproliferative disorder (MPD) that, over time, progresses to acute leukemia. Both processes are closely associated with the t(9;22) chromosomal translocation that creates the BCR/ABL fusion gene in hematopoietic stem cells (HSCs) and their progeny. Chronic myelo...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187741/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12890867/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1633833100 |
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