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Proteomic alterations associated with biomechanical dysfunction are early processes in the Emilin1 deficient mouse model of aortic valve disease

Aortic valve (AV) disease involves stiffening of the AV cusp with progression characterized by inflammation, fibrosis, and calcification. Here, we examine the relationship between biomechanical valve function and proteomic changes before and after the development of AV pathology in the Emilin1−/− mo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Ann Biomed Eng
Egile Nagusiak: Angel, PM, Narmoneva, DA, Sewell-Loftin, MK, Munjal, C, Dupuis, L, Landis, BJ, Jegga, A, Kern, CB, Merryman, WD, Baldwin, HS, Bressan, GM, Hinton, RB
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665708/
https://ncbi.nlm.nih.gov/pubmed/28812215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-017-1899-0
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