Proteomic alterations associated with biomechanical dysfunction are early processes in the Emilin1 deficient mouse model of aortic valve disease

Aortic valve (AV) disease involves stiffening of the AV cusp with progression characterized by inflammation, fibrosis, and calcification. Here, we examine the relationship between biomechanical valve function and proteomic changes before and after the development of AV pathology in the Emilin1−/− mo...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Ann Biomed Eng
Главные авторы: Angel, PM, Narmoneva, DA, Sewell-Loftin, MK, Munjal, C, Dupuis, L, Landis, BJ, Jegga, A, Kern, CB, Merryman, WD, Baldwin, HS, Bressan, GM, Hinton, RB
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665708/
https://ncbi.nlm.nih.gov/pubmed/28812215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-017-1899-0
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы