Proteomic alterations associated with biomechanical dysfunction are early processes in the Emilin1 deficient mouse model of aortic valve disease

Aortic valve (AV) disease involves stiffening of the AV cusp with progression characterized by inflammation, fibrosis, and calcification. Here, we examine the relationship between biomechanical valve function and proteomic changes before and after the development of AV pathology in the Emilin1−/− mo...

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Detaylı Bibliyografya
Yayımlandı:Ann Biomed Eng
Asıl Yazarlar: Angel, PM, Narmoneva, DA, Sewell-Loftin, MK, Munjal, C, Dupuis, L, Landis, BJ, Jegga, A, Kern, CB, Merryman, WD, Baldwin, HS, Bressan, GM, Hinton, RB
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665708/
https://ncbi.nlm.nih.gov/pubmed/28812215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-017-1899-0
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