Iron affects Ire1 clustering propensity and the amplitude of endoplasmic reticulum stress signaling

The unfolded protein response (UPR) allows cells to adjust secretory pathway capacity according to need. Ire1, the endoplasmic reticulum (ER) stress sensor and central activator of the UPR is conserved from the budding yeast Saccharomyces cerevisiae to humans. Under ER stress conditions, Ire1 cluste...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Cohen, Nir, Breker, Michal, Bakunts, Anush, Pesek, Kristina, Chas, Ainara, Argemí, Josepmaria, Orsi, Andrea, Gal, Lihi, Chuartzman, Silvia, Wigelman, Yoav, Jonas, Felix, Walter, Peter, Ernst, Robert, Aragón, Tomás, van Anken, Eelco, Schuldiner, Maya
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665437/
https://ncbi.nlm.nih.gov/pubmed/28794014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.201715
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