Iron affects Ire1 clustering propensity and the amplitude of endoplasmic reticulum stress signaling

The unfolded protein response (UPR) allows cells to adjust secretory pathway capacity according to need. Ire1, the endoplasmic reticulum (ER) stress sensor and central activator of the UPR is conserved from the budding yeast Saccharomyces cerevisiae to humans. Under ER stress conditions, Ire1 cluste...

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Publicat a:J Cell Sci
Autors principals: Cohen, Nir, Breker, Michal, Bakunts, Anush, Pesek, Kristina, Chas, Ainara, Argemí, Josepmaria, Orsi, Andrea, Gal, Lihi, Chuartzman, Silvia, Wigelman, Yoav, Jonas, Felix, Walter, Peter, Ernst, Robert, Aragón, Tomás, van Anken, Eelco, Schuldiner, Maya
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665437/
https://ncbi.nlm.nih.gov/pubmed/28794014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.201715
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