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Molecular Evaluation of Endoplasmic Reticulum Homeostasis Meets Humoral Immunity

The biosynthesis of about one third of the human proteome, including membrane receptors and secreted proteins, occurs in the endoplasmic reticulum (ER). Conditions that perturb ER homeostasis activate the Unfolded Protein Response (UPR). An ‘optimistic’ UPR output aims at restoring homeostasis by re...

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Detalhes bibliográficos
Publicado no:Trends Cell Biol
Main Authors: van Anken, Eelco, Bakunts, Anush, Hu, Chih-Chi Andrew, Janssens, Sophie, Sitia, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611675/
https://ncbi.nlm.nih.gov/pubmed/33685797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2021.02.004
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